(±)-α-LIPOIC ACID

(±)-α-Lipoic acid

(±)-α-Lipoic acid

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(±)-α-Lipoic Acid


(±)-α-Lipoic acid, also known as thioctic acid, is a naturally occurring organosulfur compound derived from octanoic acid. It serves as a coenzyme in mitochondrial energy metabolism and functions as a potent antioxidant, capable of neutralizing free radicals and regenerating other antioxidants like glutathione, vitamin C, and vitamin E. Due to its fat- and water-soluble properties, α-lipoic acid can work in various biological environments, making it highly effective in metabolic and neuroprotective applications.




Applications of (±)-α-Lipoic Acid


1. Pharmaceutical and Nutraceutical Uses

  • Supports mitochondrial function by participating in enzymatic energy production.

  • Additionally, it reduces oxidative stress and improves cellular defense mechanisms.

  • Commonly used in dietary supplements for neuropathy, diabetes, and anti-aging benefits.

  • Moreover, it enhances insulin sensitivity, making it valuable in diabetes management.


2. Antioxidant and Anti-Inflammatory Applications

  • Neutralizes free radicals, reducing oxidative damage to cells and tissues.

  • Furthermore, it recycles and enhances the effectiveness of glutathione, vitamin C, and vitamin E.

  • Additionally, it reduces inflammation, benefiting conditions such as neurodegenerative diseases and cardiovascular health.


3. Cosmetic and Dermatological Formulations

  • Incorporated in anti-aging creams and serums due to its ability to reduce wrinkles and fine lines.

  • Moreover, it protects skin against UV radiation and environmental stressors.

  • Additionally, it enhances skin elasticity by supporting collagen production.


4. Industrial and Research Applications

  • Used as a biochemical reagent in research studies related to metabolism and cellular signaling.

  • Furthermore, it is investigated for its potential in heavy metal detoxification due to its ability to chelate harmful metals.

  • Additionally, it is studied for its neuroprotective effects in conditions like Alzheimer’s and Parkinson’s disease.


Features and Benefits



  • Powerful Antioxidant: Effectively neutralizes free radicals and supports antioxidant regeneration

  • Metabolic Support: Plays a crucial role in mitochondrial energy production

  • Dual Solubility: Functions in both lipid and aqueous environments for versatile activity

  • Neuroprotective Effects: May aid in reducing nerve damage and improving cognitive function

  • Skin and Cellular Health: Protects against oxidative stress and enhances collagen stability


Safety and Handling



  • Store in a cool, dry place, away from heat and direct sunlight

  • Use protective gloves and eyewear when handling in industrial or laboratory settings

  • Follow proper disposal procedures for laboratory and pharmaceutical applications

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